Table 3.
Proportion of participants with epilepsy who responded “yes” to “Do you think you would have wanted more (or any) children if you had not had epilepsy?” by demographic variables, epilepsy-related variables, number of affected family members, genetic attribution scale and risk estimates
| na | % yes | p-value | PR (95% CI) | |
|---|---|---|---|---|
| All participants with epilepsy | 148 | 18.9% | n/a | n/a |
| Women | 86 | 25.6% | 0.02 | 2.6 (1.15–6.06) |
| Men | 62 | 9.7% | (ref.) | 1.0 (ref.) |
| Age 18–34 years | 28 | 25.0% | 0.36 | 1.5 (0.63–3.60) |
| Age 35–49 years | 42 | 19.0% | 0.74 | 1.1 (0.53–2.49) |
| Age ≥50 years | 78 | 16.7% | (ref.) | 1.0 (ref.) |
| College graduate or higher | 80 | 21.3% | 0.43 | 1.3 (0.68–2.46) |
| Less than college graduate | 67 | 16.4% | (ref.) | 1.0 (ref.) |
| Catholic | 30 | 13.3% | 0.36 | 0.6 (0.15–1.96) |
| Protestant | 51 | 19.6% | 0.63 | 0.8 (0.35–1.89) |
| Otherb | 28 | 21.4% | 0.79 | 0.9 (0.35–2.21) |
| None/atheist/prefer not to say | 33 | 24.2% | (ref.) | 1.0 (ref.) |
| Ever married | 110 | 19.1% | 0.92 | 1.0 (0.50–2.15) |
| Never married | 38 | 18.4% | (ref.) | 1.0 (ref.) |
| Last seizure <5 years ago | 68 | 25.0% | 0.29 | 1.5 (0.71–3.19) |
| Last seizure ≥5 years ago | 54 | 16.7% | (ref.) | 1.0 (ref.) |
| Lifetime number of seizures | ||||
| >100 | 27 | 40.7% | 0.01 | 2.9 (1.32–6.37) |
| 21–100 | 28 | 14.3% | 0.98 | 1.0 (0.36–2.91) |
| ≤20 | 64 | 14.1% | (ref.) | 1.0 (ref.) |
| Total number of affected family members | ||||
| ≥4 | 61 | 27.9% | 0.04 | 2.2 (1.04–4.77) |
| <4 | 80 | 12.5% | (ref.) | 1.0 (ref.) |
| Genetic attribution scalec | ||||
| High (3) | 46 | 19.6% | 0.10 | 3.5 (0.78–15.88) |
| Moderate (2–2.9) | 66 | 25.8% | 0.03 | 4.6 (1.19–18.01) |
| Low (<2) | 36 | 5.6% | (ref.) | 1.0 (ref.) |
| Participant’s estimate of risk of epilepsy in offspring of affected parent | ||||
| ≥50% | 38 | 21.1% | 0.40 | 0.7 (0.31–1.61) |
| 25–49% | 21 | 19.0% | 0.37 | 0.6 (0.23–1.72) |
| 10–24% | 35 | 11.4% | 0.08 | 0.4 (0.13–1.14) |
| <10% | 30 | 30.0% | (ref.) | 1.0 (ref.) |
PR, prevalence ratio, CI, confidence interval, ref., referent
Total n’s vary among different variables because of missing data.
Other religions listed as Jewish, Hindu, Buddhist, or “Other.”
Genetic attribution questions, each coded from 1 to 3: “In your opinion, how big a role has genetics had in causing the epilepsy in your family?” “In your opinion, what do you think the chances are that you have a change or mutation in a gene that affects risk for epilepsy?” and “How much do you think genetics or inheritance influenced your risk of developing epilepsy?” Scale values were obtained by averaging the responses to the three questions and then categorized.