Figure 2: Cerebral Mitochondrial Respiration and Reactive Oxygen Species Generation.
Box plots represent measurements from cerebral cortex (top panel) and hippocampus (bottom panel): A and E, Complex I oxidative phosphorylation; B and F, maximal oxidative phosphorylation (Complex I + Complex II); C and G, leak respiration; and D and H, mitochondrial reactive oxygen species (Complex I + Complex II). Respiration values are provided in pmol O2/s*mg. Reactive oxygen species are provided in pmol H2O2/s*mg. Displayed values were normalized to citrate synthase content and were compared between groups using the Wilcoxon rank-sum test. *Indicates statistically significant (p<0.05) difference between groups.
