Table 2.
Regions showing altered nodal centralities in patients with early-stage Parkinson’s disease compared with healthy controls
| Brain regions | P value (Cohen’s d) | ||
|---|---|---|---|
| Nodal betweenness | Nodal degree | Nodal efficiency | |
| Parkinson’s disease < Healthy controls | |||
| Left gyrus rectus | 0.0164 (− 0.384) | 0.0002 (− 0.787) | 0.0002 (− 0.787) |
| Right superior occipital gyrus | 0.0026 (− 0.556) | 0.0990 (− 0.247) | 0.1320 (− 0.214) |
| Left postcentral gyrus | 0.1250 (0.229) | 0.0026 (− 0.558) | 0.0012 (− 0.568) |
| Right postcentral gyrus | 0.1348 (0.220) | 0.0024 (− 0.573) | 0.0022 (− 0.589) |
| Right inferior temporal gyrus | 0.1856 (− 0.177) | 0.0024 (− 0.561) | 0.0016 (− 0.575) |
| Parkinson’s disease > Healthy controls | |||
| Right superior frontal gyrus, orbital part | 0.0780 (0.271) | 0.0004 (0.675) | 0.0004 (0.653) |
| Left putamen | 0.0056 (0.477) | 0.0024 (0.591) | 0.0004 (0.625) |
Regions were considered abnormal in patients if they exhibited significant between-group differences (P < 0.05, FDR corrected) in at least one of the three nodal centralities (shown in bold font)