Fig. 2.

Effects of 4-CMC (5, 10, 20 mg/kg) and 4-MeO-PVP (5, 10, 20 mg/kg) on spontaneous locomotor activity of mice. Average horizontal a, c and vertical b, d activities in 10-min bins. Data are presented as mean ± standard error of the mean (SEM) (n = 7–8). ***p < 0.001; **p < 0.01; *p < 0.05 vs. control group; two-way repeated measures ANOVA, Dunnett’s post hoc test. Total distance traveled during 120 min e. Total rearing counts during 120 min f. Data are presented as mean ± standard error of the mean (SEM) (n = 7–8). ***p < 0.001; **p < 0.01; *p < 0.05 vs. control group; ###p < 0.001; ##p < 0.01; #p < 0.05 between indicated groups; one-way ANOVA, Tukey’s post hoc test