Table 3.

Cox regression analysis of WT1 mutations and other prognostic factors.

Outcome	Variable	Hazard ratio (95% CI)	P-value
EFS	WT1	1.910(1.297-2.812)	0.001
	High risk	3.136(2.235-4.400)	<0.001
	Standard risk	2.581(2.207-3.286)	<0.001
	HSCT	0.431(0.313-0.593)	<0.001
	Age > 10 years	1.300(1.053-1.607)	0.015
	WBC>50×109/L	1.499(1.220-1.841)	<0.001
OS	WT1	1.709(1.090-2.679)	0.02
	High risk	3.991(2.653-6.004)	<0.001
	Standard risk	3.413(2.494-4.670)	<0.001
	HSCT	0.594(0.419-0.843)	0.004
	Age > 10 years	1.496(1.158-1.933)	0.002
	WBC>50×109/L	1.307(1.018-1.677)	0.036

CI, confidence interval; EFS, event-free survival; HSCT, hematopoietic stem cell transplantation; OS, overall survival; WBC, white blood cell count.