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. 2021 Apr 21;12:652985. doi: 10.3389/fimmu.2021.652985

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Copyright © 2021 Qing, Lu, Liu, Wen, Chen, Lin, Ma, Zhao, Liu and Tan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Imaging, histologic and laboratory findings of the case. (A) The abduction of both eyes was limited (arrows indicate the direction of movement), and contrast-enhancing brain magnetic resonance imaging (MRI) showed a 3.8×2.9×2.9 cm mass overlying clivus with dural tail sign (arrow head). (B) Abduction of both eyes recovered after treatment and MRI showed the mass in the clivus area was remarkably smaller. (C) Histologic features of the lesion revealed fibro-connective tissue with mixed inflammation containing predominantly plasma cells and immunochemical analysis revealed an increased number of IgG4-positive plasma cells (×200). (D, E) Serum levels of IgG and IgG4 (D) and T cell-released INF-γ in TB-IGRA (E) of the patient during the follow-up.