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. 2021 May 5;39(6):653–665. doi: 10.1007/s40273-021-01019-4

Table 1.

Prevalence, employment, and treatment rates of MDD

A. Prevalence of adults with MDD in past year by employment statusa
Status 2010b 2018 Change (2010–2018)c
All adults Adults with MDD Prevalence rate (%) All adults Adults with MDD Prevalence rate (%) Adults with MDD Prevalence rate (%)
Employed full-time 114,023,964 6,274,910 5.5 122,542,772 7,696,432 6.3 1,421,523 0.8
Employed part-time 33,056,026 2,312,373 7.0 31,859,894 2,798,607 8.8 486,233 1.8
Not employed 81,438,556 6,946,896 8.5 91,634,491 7,018,244 7.7 71,348 − 0.9
Total 228,518,546 15,534,179 6.8 246,037,157 17,513,283 7.1 1,979,104 0.3
B. Treatment rate of adults with MDD in past year by employment statusa,d
2010 2018 Change (2010–2018)
No. of treated cases Rate (%) No. of treated cases Rate (%) No. of treated cases Change in rate (%)
Employed full-time 3,225,244 51.5 4,158,136 54.0 932,892 2.5
Employed part-time 1,136,974 49.3 1,441,642 51.7 304,668 2.4
Not employed 4,329,892 62.3 4,120,908 58.8 − 208,984 − 3.5
Total 8,692,110 56.0 9,720,686 55.6 1,028,576 − 0.5

MDD major depressive disorder, NSDUH National Survey on Drug Use and Health

Data source: US Department of Health and Human Services. National Survey on Drug Use and Health, public-use files, 2010 and 2018 [11]

aIn 2010 and 2018, MDD in past year is based on the variable AMDDEYR (“Adult: past year major depressive episode”). In 2010, employment status is based on the variable EMPSTAT4 (“Imputation revised employment status 18+”). In 2018, employment status is based on the variable IRWRKSTAT (“Employment status—imputation revised”). Results are weighted based on the variable ANALWT_C (“Final person-level sample weight”) for 2018 and on the variable AWTC10_C (“2010 analysis weight poststratified to 2010 census totals”) for 2010. Adults with unknown MDD status were excluded from analysis

bValues for 2010 varied slightly from previously published results because of ongoing revisions of the NSDUH data. Values for 2010 varied further because of the use of an updated weighting variable relative to previously published results. None of the study conclusions were impacted by the variations

cp < 0.001 for all changes. p values for the change across years are calculated using the two-sample z test for independent proportions

dTreatment rate was identified based on the variable AMHTXRC3 (“Received any mental health treatment in past year”)