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. 2021 Apr 21;12:608875. doi: 10.3389/fimmu.2021.608875

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Copyright © 2021 Dasilva, Lois, Méndez, Miralles-Pérez, Romeu, Ramos-Romero, Torres and Medina

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of lipid mediators formed in the perigonal adipose tissue of rats fed STD, STD+ω3, HFHS or HFHS+ω3 diets. (A). Balance of several EPA/ARA LOX-Hydroxides, particularly, 5HEPE/5HETE, 12HEPE/12HETE and 15HEPE/15HETE measured in adipose tissue from rats fed STD, STD+ω3, HFHS or HFHS+ω3 diets. (B). Balance of several Hydroxides/Hydroperoxides from EPA, particularly 12HEPE/12HpHEPE and 15HEPE/15HpHEPE, measured in in adipose tissue from rats fed STD, STD+ω3, HFHS or HFHS+ω3 diets. (C). Percentage of 11HETE in total ARA Hydroxides and percentage of 11HEPE in total EPA Hydroxides measured in adipose tissue from rats fed STD or HFHS diets. (D). Percentage of several DHA Hydroxides, particularly 4HDoHE, 11HDoHE, 14HDoHE and17HDoHE, in total LOX-Hydroxides measured in adipose tissue from rats fed STD or HFHS diets (n=9 per group). *Significant differences among groups (p < 0.05).