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. 2021 Apr 18;21(6):647. doi: 10.3892/etm.2021.10079

Figure 3.

Figure 3

SINO treatment mitigates MCAO-associated inflammation and oxidative stress. (A) RT-sqPCR analysis of TNF-α and IL-1β mRNA expression levels in brain tissues. The results of two samples from each group were presented. (B) RT-sqPCR analysis of NOS2 mRNA expression levels in brain tissues. (C) The relative enzyme activities of GPx from the brain tissue of the four groups. (D) The relative enzyme activities of SOD from the brain tissue of four groups. All experiments were repeated at least three times. The data are presented as the mean ± SEM. *P<0.05 and **P<0.01 vs. Sham; #P<0.05 and ##P<0.01 vs. MCAO. GPx, glutathione peroxidase; MCAO, middle cerebral artery occlusion; NOS2, nitric oxide synthase 2; RT-sqPCR, reverse transcription-semi-quantitative PCR; SINO, sinomenine; SOD, superoxide dismutase.