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Humoral and mucosal immune responses elicited by EBY100/pYD1-RBD. a RBD-specific serum IgG titers (n = 10 mice/group). b Secretory IgA in the feces (n = 10 mice/group). The data shown are the means ± SDs of three technical replicates per measurement, and the asterisks indicate significant differences compared with the PBS- and EBY100/pYD1-vaccinated controls. *p < 0.05, **p < 0.01
