Table 2.
3D structural details of human cell receptors that bind with coronaviruses (SARS-CoV, SARS-CoV-2, and MERS-CoV)
(Source: https://www.rcsb.org/)
| PDB entry | Method | Resolution (Å) | Chains | Sequence position | Sequence length |
|---|---|---|---|---|---|
| ACE2 | |||||
| 1R42 | X-ray | 2.20 | A | 1–615 | 614 |
| 1R4L | X-ray | 3.00 | A | 1–615 | 614 |
| 6M0J | X-ray | 2.45 | A | 19–615 | 596 |
| 6M17 | EM | 2.90 | B/D | 18–805 | 787 |
| DPP4 | |||||
| 1J2E | X-ray | 2.60 | A/B | 33–766 | 733 |
| 1PFQ | X-ray | 1.90 | A/B | 36–766 | 730 |
| 4A5S | X-ray | 1.62 | A/B | 39–766 | 727 |
| 4N8D | X-ray | 1.65 | A/B | 39–766 | 727 |
| CD147 | |||||
| 3I84 | X-ray | 2.00 | A/B | 13–219 | 206 |
| 4U0Q | X-ray | 3.10 | B/D | 1–385 | 384 |
| CD209L | |||||
| 1SL6 | X-ray | 2.25 | A/B/C/D/E/F | 216–399 | 183 |
| 1XAR | X-ray | 2.25 | A/B | 216–399 | 183 |
| 1XPH | X-ray | 1.41 | A | 250–399 | 149 |
ACE2 angiotensin-converting enzyme 2, DPP4 dipeptidyl peptidase 4, PDB Protein Data Bank, EM electron microscopy