Characterizations of LDH, Cu‐LDH, and Cu‐LDH/HMME@Lips. a) TEM image of LDHs, scale bar, 100 nm. b) TEM image of Cu‐LDH, scale bar, 50 nm. c) XRD spectra of LDHs and Cu‐LDH. d) TEM image of Cu‐LDH/HMME@Lips, scale bar, 500 nm. Insert, SEM images of Cu‐LDH/HMME@Lips, scale bar 100 nm, and e) corresponding energy‐dispersive X‐ray spectrum. f) UV–vis absorbance spectra of Lips, HMME, Cu‐LDH, HMME@Lips, and Cu‐LDH/HMME@Lips, indicating the successful encapsulation of Cu‐LDH and HMME into the liposomes. g) TEM images of Cu‐LDH/HMME@Lips before (up) and after (down) US irradiation. scale bar, 200 nm. h) Hydrodynamic diameters of Cu‐LDH and Cu‐LDH/HMME@Lips before and after US irradiation in PBS measured by DLS. i) Zeta potentials of Cu‐LDH, Lips, Cu‐LDH/HMME@Lips, and Cu‐LDH/HMME@Lip after US irradiation and washed with ethanol, error bars are based on SD (n = 3). Insert: digital photos of different corresponding solutions showing distinct Tyndall effects.