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. 2021 Feb 25;8(9):2003535. doi: 10.1002/advs.202003535

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© 2021 The Authors. Advanced Science published by Wiley‐VCH GmbH

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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MgFe‐LDH nanoparticles maintain the pluripotency of mECSs via LIFR/PI3K/AKT, LIFR/JAK/STAT3, and p‐STAT3/TET pathways. A) Bright‐field images of mESCs cultured for 3 d in media containing LIF/LIFR inhibitor EC359. B) Western blot was applied to measure protein expression changes in mESCs cultured for 3 d on gelatin, with or without EC359, subjected to the requisite treatment. C) Analysis of changes in mRNA expression following EC359 treatment via qPCR. * represents p < 0.05, when compared to the LIF‐group. D) Global 5mc and 5hmc levels detected by dot blot.