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. 2021 Mar 18;65(4):e02479-20. doi: 10.1128/AAC.02479-20

FIG 4.

FIG 4

Tissue concentrations of AT-9010 in nonhuman primates. Cynomolgus monkeys were given a loading dose of 60 mg/kg AT-527 followed by 30 mg/kg maintenance doses every 12 h for 3 days to achieve steady state. Tissue samples were collected under anesthesia at the indicated time points after the last dose, flash frozen, and homogenized, and AT-9010 concentrations were determined by LC-MS/MS. Data are expressed as means ± SEs (n = 3).

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