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Representative time-concentration profiles for simulated human once-daily dosing regimens of anidulafungin (AFG), caspofungin (CAS), and micafungin (MFG) in an in vitro pharmacokinetic/pharmacodynamic (PK/PD) model with target maximum concentration (fCmax) of 4 mg/liter. Data represent drug levels in the internal compartment of the in vitro model (solid lines) and the respective target values observed in human serum (broken lines).
