TABLE 1.

Echinocandin MECs/MICs determined by different susceptibility testing methods^a of A. fumigatus isolates used in the present study

Antifungal	WT status of isolate	MEC/MIC (mg/liter) by:
		CLSI	EUCAST	XTT	MTS
Anidulafungin	WT
	AZN8196	0.016	0.03	0.004	0.004
	V52-35	0.016	0.03	0.008	0.008
	DPLRG101b	0.016	0.03	0.004	0.004
	Non-WT
	DPL1035-homo	4	16	16	2
	DPL32458	2	16	32	8
Caspofungin	WT
	AZN8196	0.25	0.5	0.25	0.06
	NIH 4215 (ATCC no. MYA-3626)	0.25	0.5	0.5	0.125
	AUH-25	0.25	0.5	0.5	0.25
	AUH-27	0.25	0.5	0.25	0.06
	AUH-29	0.25	0.5	0.25	0.06
	Non-WT
	DPL1035-homo	16	8	16	8
	DPL32458	16	4	8	2
	DPLRG101b	8	4	8	2
Micafungin	WT
	AZN8196	0.016	0.03	0.008	0.004
	V52-35	0.016	0.03	0.008	0.004
	DPLRG101b	0.016	0.03	0.008	0.004
	Non-WT
	DPL1035-homo	1	4	8	0.5
	DPL32458	8	8	8	1

^aBroth microdilution (CLSI, EUCAST, and XTT) and gradient concentration strips (MTS).

^bDemonstrated a non-WT phenotype only to caspofungin.