TABLE 1.
MICs and minimal biofilm eradication concentrationsa
| Antibiotic | Assay | MIC or MBEC value (mg/liter) |
|||||
|---|---|---|---|---|---|---|---|
| ATCC 33591 |
ATCC 35984 |
ATCC 47076b |
|||||
| MHB-ca | TGN | MHB-ca | TGN | MHB-ca | TGN | ||
| Daptomycin | MIC | 1 | 1 | 1 | 1 | ||
| MBEC | 4 | >1,024 | >1,024 | >1,024 | |||
| Doxycycline | MIC | 16 | 16 | 0.25 | 0.25 | ||
| MBEC | 128 | 512 | |||||
| Linezolid | MIC | 2 | 1 | 2 | 1 | ||
| MBEC | 8 | >1,024 | >1,024 | >1,024 | |||
| Moxifloxacin | MIC | 0.125 | 0.125 | 0.06 | 0.125 | ||
| MBEC | 2 | >1,024 | >1,024 | >1,024 | |||
| Rifampin | MIC | 0.004 | 0.004 | 0.004 | 0.004 | ||
| MBEC | 8 | 2 | 128 | 4 | |||
| Vancomycin | MIC | 1 | 8 | 2 | 8 | ||
| MBEC | >1,024 | >1,024 | >1,024 | >1,024 | |||
| Ceftazidime | MIC | 0.25 | 0.125 | ||||
| MBEC | >1,024 | ||||||
| Ciprofloxacin | MIC | 0.016 | 0.03 | ||||
| MBEC | 128 | ||||||
| Colistin | MIC | 0.5 | 0.25 | ||||
| MBEC | >1,024 | ||||||
| Meropenem | MIC | 0.03 | 0.06 | ||||
| MBEC | >256 | ||||||
a
Values in bold indicate an MIC superior to the CLSI breakpoint values (50).
b
The MBEC assay results for the ATCC 47076 strain were unreliable and were not included.