Schematic representation of the sphingolipid pathways in fungi. All of these reactions are reversible. A dotted line means additional enzymatic steps are present but are not illustrated for clarity. DHS, dihydrosphingosine; PHS, phytosphingosine; DHS-1-P, dihydrosphingosine-1-phosphate; PHS-1-P, phytosphingosine-1-phosphate; DHC, dihydroceramide; PHC, phytoceramide; CER, ceramide; OH-PHC, hydroxylated-phytoceramide; OH-CER, hydroxylated ceramide; GlcCer, glucosylceramide; IPC 36, inositol phosphoryl ceramide containing 36 carbons (sphingoid base plus fatty acid); IPC 42, inositol phosphoryl ceramide containing 42 carbons (sphingoid base plus fatty acid); IPC-44, inositol phosphoryl ceramide containing 44 carbons (sphingoid base plus fatty acid).