FIG 3.

Graphical representation of time to putative IC₅₀ (T-IC₅₀), time above IC₅₀ (T>IC₅₀), time to putative IC₉₀ (T-IC₉₀), and time above IC₉₀ (T>IC₉₀) after rectal artesunate administration. Concentrations were measured as the sum of molar artesunate and dihydroartemisinin concentrations. Markers represent individual values and lines represent the median value and its interquartile range. The graphic shows only data for patients who reached the cutoff (IC₅₀ or IC₉₀). One patient did not reach IC₅₀. The red dots indicate the 2 cases with a longer time to reach IC₉₀.