TABLE 2.
Summary of parasite clearance time by study arm
| Parameter | RASf | IVASf | P value |
|---|---|---|---|
| No. of individual profiles analyzed | 35 | 40 | |
| Slope half-life, h | 0.64 | ||
| Median | 2.2 | 2.5 | |
| Range | 1.3–7.6 | 1.2–12.0 | |
| GM (95% CI) | 2.3 (2.0; 2.6) | 2.43 (2.1; 2.8) | |
| t-lag, h | 0.81 | ||
| Median | 0 | 0 | |
| Range | 0–12 | 0–24 | |
| IQR | 0–6 | 0–6 | |
| GM (95% CI) | 6.9 (5.9–8.1); n = 5 | 8.3 (6.2, 11.0); n = 15 | |
| Median pc50 (range), h | 7.1 (0.3, 15.1) | 6.8 (0.4, 24.4) | 0.28 |
| Median pc90 (range), h | 11.8 (4.1, 25.7) | 13.9 (3.5, 41.8) | 0.16 |
| Median pc95 (range), h | 14.0 (5.7, 33.3) | 16.8 (4.8, 53.8) | 0.13 |
| Median pc99 (range), h | 18.8 (9.1, 50.8) | 22.1 (7.8, 81.7) | 0.14 |