TABLE 3.
Lung and spleen CFU counts at the indicated time points (values are means ± SD, standard deviation, n = 5)
| Log CFU |
Log CFU (4 wk) |
Log CFU (8 wk) |
||||
|---|---|---|---|---|---|---|
| Groups | Lung | Spleen | Lung | Spleen | Culture negativea |
|
| Lung | Spleen | |||||
| D-28 | 2.77 ± 0.56 | 0 | ||||
| D-14 | 5.20 ± 0.24 | 3.29 ± 0.45 | ||||
| D0 | 6.81 ± 0.67 | 4.16 ± 0.44 | ||||
| Control | 5.76 ± 0.14 | 4.86 ± 0.33 | ||||
| TBI-166, QD | 4.05 ± 0.23 | 3.72 ± 0.27 | 4/5 | 3/5 | ||
| TBI-66, TIW | 4.18 ± 0.21 | 3.22 ± 0.62 | 5/5 | 3/5 | ||
| CLO, QD | 3.72 ± 0.17 | 3.18 ± 0.17 | 3/5 | 3/5 | ||
| CLO, TIW | 4.19 ± 0.50 | 3.31 ± 0.34 | 5/5 | 3/5 | ||
a
number of mice with culture negative lung and spleen by 8 weeks.