Figure 12.

Schematic representation of the proposed updated version of the wiring scheme of the parahippocampal‐hippocampal system. The lateral and medial entorhinal cortex mediate parallel input streams, conveying integrated representations of two complementary sets of cortical inputs to the hippocampus. The lateral entorhinal cortex (LEC) receives strong inputs from perirhinal (PER), orbitofrontal, medial prefrontal and insular cortices (PFC), and olfactory structures (OLF) including the olfactory bulb and the olfactory or piriform cortex. In contrast, MEC receives main inputs from presubiculum (PRS), parasubiculum (PAS), and retrosplenial cortex (RSC). The postrhinal/parahippocampal cortex (POR/PHC) provides inputs to both MEC and LEC as well as to PER. Dashed dividers in boxes imply that incoming projections distribute to both components of the box. CA3, CA2, CA1, subfields of the hippocampus proper; DG, dentate gyrus; dist, distal part; prox, proximal part [Color figure can be viewed at wileyonlinelibrary.com]