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. Author manuscript; available in PMC: 2022 Jun 1.

Published in final edited form as: Bone. 2021 Mar 11;147:115908. doi: 10.1016/j.bone.2021.115908

Table 2.

Gambogic amide increases load-induced bone formation.

GA
	PS.MS/BS (μm/μm)	Es.MS/BS (μm/μm)	Ps.MAR (μm/day)	Es.MAR (μm/day)	Ps.BFR/BS (μm³/μm²/day)	Es.BFR/BS (μm³/μm²/day)
Loaded	0.41 ± 0.12^*	0.80 ± 0.09^*	1.16 ± 0.66^* ⁺	1.35 ± 0.51^*	0.43 ± 0.16^* ⁺	1.12 ± 0.47^*
Non-Loaded	0.22 ± 0.15	0.64 ± 0.12	0.29 ± 0.13	0.67 ± 0.26	0.08 ± 0.07	0.41 ± 0.16
Vehicle
	PS.MS/BS (μm/μm)	Es.MS/BS (μm/μm)	Ps.MAR (μm/day)	Es.MAR (μm/day)	Ps.BFR/BS (μm³/μm²/day)	Es.BFR/BS (μm³/μm²/day)
Loaded	0.35 ± 0.12^*	0.72 ± 0.22	0.68 ± 0.18^*	1.06 ± 0.38^*	0.25 ± 0.12^*	0.76 ± 0.38^*
Non-Loaded	0.19 ± 0.12	0.52 ± 0.23	0.15 ± 0.08	0.46 ± 0.17	0.03 ± 0.03	0.25 ± 0.12

Values are presented as mean ± standard deviation.

^*

p < 0.05 vs. non-loaded,

⁺

p < 0.05 vs. vehicle by two-way ANOVA.

n=7 per group.