TABLE 3.
Univariable analysis of factors potentially associated with disease-specific survival in patients who received immunotherapy (n = 29)
| Variable (n) | Median survival (mo.) |
5-year survival (%) |
p |
|---|---|---|---|
| Age | |||
| ≤60 y (16) | 54.8 | 42 | 0.52 |
| >60 y (13) | NR | 55 | |
| Sex | |||
| Female (13) | 37.5 | 37.5 | 0.94 |
| Male (16) | 88.5 | 51 | |
| Presentation | |||
| Anemia (14) | 54.8 | 41 | 0.45 |
| Mass (11) | 88.5 | 57 | |
| Pain (1) | NR | NR | |
| Colonoscopy (3) | 18.9 | NR | |
| Site or origin | |||
| Anorectal (15) | 88.5 | 70 | 0.42 |
| Perianal (7) | 54.8 | NR | |
| Rectum (7) | 30.6 | 43 | |
| Ballantyne stage | |||
| I (18) | 88.5 | 52 | 0.58 |
| II (11) | NR | 51 | |
| Type of Surgery | |||
| APR (8) | 27.6 | 19 | 0.19 |
| LE (21) | 88.5 | 65 | |
| Margins | |||
| R0 (15) | 37.5 | 48 | 0.49 |
| R1/2 (13) | NR | 58 | |
| LVI | |||
| Yes (11) | 23.4 | 50 | 0.17 |
| No (7) | NR | 71 | |
| PNI | 0.16 | ||
| Yes (3) | NR | 33 | |
| No (9) | 30.6 | 77 | |
| Depth | |||
| ≥10 mm (13) | NR | 55 | 0.58 |
| <10 mm (12) | 54.8 | 20 | |
| Systemic chemotherapy | |||
| Yes (13) | 30.6 | 39 | 0.43 |
| No (16) | 88.5 | 61 | |
| Locoregional radiation | |||
| Yes (8) | 88.5 | 52 | 0.96 |
| No (21) | NR | 52 |
NR, not reached; APR, abdominoperineal resection; LE, local excision; LVI, lymphovascular invasion; PNI, perineural invasion.