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Overexpression of miR-146a reduced depression behaviors in LPS-induced mice. (A) miR-146a expression in every group. (B) Sucrose preference (C) Forced swimming test (D) Tail suspension test. (E) Locomotor activity. *P<0.05 and **P<0.01 vs. control group; ##P<0.01 vs. LPS group; &&P<0.01 vs. mimic-NC group; %%P<0.01 vs. siRNA-NC group. miR, microRNA; LPS, lipopolysaccharide; NC, negative control; si, short interfering.
