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Overexpression of miR-146a repressed depression behaviors in CUMS mice. (A) miR-146a expression of mice. (B) Sucrose preference. (C) Forced swimming test. (D) Tail suspension test. (E) Locomotor activity. **P<0.01 vs. control group; ^^P<0.01 vs. CUMS group; @@P<0.01 vs. mimic-NC + CUMS group; $$P<0.01 vs. siRNA-NC + CUMS group. miR, microRNA; CUMS, chronic unpredictable mild stress; NC, negative control; si, short interfering.
