Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 5;21:249. doi: 10.1186/s12935-021-01953-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 3 — RAD51 associates with ovarian cancer. In UALCAN, 557 genes correlated with RAD51 in TCGA ovarian cancer. Enrichment analysis was performed using these 557 genes. a Gene Ontology pathways involved in DNA damage repair and drug responsiveness were shown. b KEGG pathways implicated in DNA damage repair and drug responsiveness were depicted. In NCBI, 209 genes interacted with RAD51. These 209 genes overlapped with the 557 genes correlated with RAD51, producing 36 overlapping genes. c Venn diagram of these 209 genes and the 557 genes correlated with RAD51 (Chi-squared test). d The protein–protein interaction network of RAD51 with the 36 overlapping genes was constructed, and interaction confidence was calculated. e Based on computation of similar target-to-disease connections and overall association scores, the targets related to RAD51 were examined in the Open Targets platform and the top 20 targets were depicted in detail