Table 3.
Association between HLA-G alleles as their low-resolution groups and risk factors for HPV infection recorded by the baseline questionnaire
| Risk factors | HLA-G alleles OR (95%Cl) |
HLA-G groups OR (95%Cl) |
||||||
|---|---|---|---|---|---|---|---|---|
| *01:01:01 | *01:01:02 | *01:01:03 | *01:03:01 | *01:04:01 | *01:06 | G01:01 | G04:01 | |
| Miscarriages (≥1) (n = 39) | 0.56 (0.25–1.29) | 1.67 (0.83–3.35) | 1.51 (0.53–4.28) | 2.87 (0.71–11.65) | 0.59 (0.22–1.60) | 0.63 (0.08–5.03) | 0.62 (0.07–5.74) | 0.56 (0.21–1.52) |
| Infertility (n = 24) | 0.44 (0.17–1.13) | 2.28 (0.97–5.34) | 0.38 (0.05–2.95) | 1.19 (0.14–9.80) | 0.78 (0.26–2.38) | NC | NC | 0.74 (0.24–2.27) |
| Infertility treatments (n = 15) | 0.37 (0.12–1.15) | 2.34 (0.81–6.77) | 0.65 (0.08–5.11) | NC | 2.11 (0.69–6.45) | NC | 0.22 (0.02–2.08) | 2.01 (0.66–6.13) |
| Sexually transmitted diseases (HSV, Chlamydia) (n = 63) | 1.12 (0.51–2.47) | 0.62 (0.34–1.13) | 1.00 (0.39–2.58) | 0.44 (0.54–3.52) | 0.75 (0.35–1.57) | 0.89 (0.19–4.22) | 0.37 (0.06–2.24) | 0.82 (0.40–1.68) |
| Self reported warts | ||||||||
| Genital (n = 80) | 0.92 (0.45–1.87) | 1.08 (0.63–1.84) | 0.67 (0.26–1.72) | 1.10 (0.28–4.35) | 1.85 (0.99–3.46) | 0.56 (0.12–2.63) | 0.39 (0.05–2.79) | 1.91 (1.03–3.53) |
| Oral (n = 8) | 1.35 (0.16–11.25) | 4.82 (0.96–24.36) | 3.21 (0.62–16.77) | 4.07 (0.45–36.75) | NC | NC | NC | NC |
| Skin (n = 166) | 1.35 (0.73–2.50) | 0.90 (0.57–1.42) | 1.86 (0.84–4.12) | 0.57 (0.16–2.08) | 0.59 (0.33–1.03) | 4.12 (0.88–19.39) | 0.76 (0.12–4.59) | 0.64 (0.37–1.12) |
| Allergies (n = 126) | 0.98 (0.51–1.87) | 0.94 (0.58–1.52) | 0.74 (0.33–1.70) | 0.29 (0.06–1.41) | 1.35 (0.75–2.43) | 2.21 (0.63–7.73) | 1.23 (0.20–7.48) | 1.35 (0.75–2.42) |
| Atopia (n = 43) | 0.51 (0.23–1.11) | 1.9 (1.00–3.73) | 1.23 (0.44–3.45) | 0.58 (0.07–4.69) | 0.93 (0.40–2.14) | 1.19 (0.25–5.69) | NC | 1.23 (0.57–2.69) |
| Vulvovaginitis (n = 48) | 0.56 (0.11–2.87) | 0.94 (0.22–4.02) | NC | 4.10 (0.45–36.89) | NC | NC | NC | NC |
| Menarche | ||||||||
| Late (>14 years) (n = 21) | 1.12 (0.31–3.99) | 0.81 (0.31–2.10) | 1.69 (0.46–6.20) | 1.55 (0.18–13.02) | 0.97 (0.31–3.01) | NC | NC | 1.25 (0.44–3.62) |
| Early (<11 years) (n = 7) | 1.18 (0.14–10.04) | 0.60 (0.11–3.17) | NC | NC | 1.57 (0.30–8.32) | 4.1 (0.45–37.35) | NC | 1.50 (0.28–7.93) |
| Start of labour | ||||||||
| Own contractions (n = 145) | 1.33 (0.69–2.59) | 0.83 (0.51–1.36) | 0.52 (0.23–1.19) | 1.19 (0.31–4.54) | 1.07 (0.59–1.95) | 2.93 (0.58–14.79) | 0.35 (0.04–3.37) | 1.02 (0.57–1.85) |
| Rupture of the membranes (n = 52) | 1.15 (0.48–2.76) | 1.22 (0.66–2.29) | 0.33 (0.75–1.43) | 0.55 (0.07–4.48) | 0.59 (0.25–1.40) | NC | 0.67 (0.07–6.58) | 0.57 (0.24–1.36) |
| Induction (n = 52) | 1.28 (0.62–2.63) | 0.70 (0.42–1.19) | 0.84 (0.35–2.01) | 1.66 (0.43–6.33) | 1.47 (0.80–2.72) | 6.48 (1.28–32.77) | 0.49 (0.07–3.51) | 1.42 (0.77–2.62) |
| Labour weeks | ||||||||
| Early (<37 weeks) (n = 8) | 0.95 (0.11–8.33) | 0.75 (0.14–4.16) | NC | NC | 0.8 (0.09–6.98) | 5.8 (0.62–54.35) | 0.07 (0.01–0.72) | 0.77 (0.09–6.69) |
| Late (>40 weeks) (n = 181) | 0.94 (0.51–1.74) | 1.05 (0.66–1.66) | 1.96 (0.87–4.43) | 1.19 (0.33–4.31) | 1.17 (0.66–2.07) | 0.44 (0.13–1.53) | 1.92 (0.32–11.66) | 1.06 (0.61–1.87) |
| Abnormal placenta (n = 9) | NC | 0.49 (0.10–2.49) | 3.21 (0.62–16.69) | NC | 0.57 (0.07–4.69) | NC | NC | 0.54 (0.07–4.50) |
The significant associations are bolded