Table 4.
Association between HLA-G genotypes and risk factors for HPV infection recorded by the baseline questionnaire
| Risk factors | HLA-G genotype OR (95% CI) |
|||||
|---|---|---|---|---|---|---|
| *010101:010101 | *010101:010102 | *010101:010103 | *010101:010401 | *010102:010102 | *010102:010401 | |
| Miscarriages (≥1) (n = 39) | 0.81 (0.37–1.75) | 1.13 (0.53–2.42) | 1.39 (0.38–5.10) | 0.50 (0.15–1.73) | 2.18 (0.42–11.24) | 0.70 (0.09–5.67) |
| Infertility (n = 24) | 1.09 (0.45–2.66) | 1.13 (0.45–2.85) | 0.70 (0.09–5.51) | 0.24 (0.03–1.84) | 1.54 (0.18–13.07) | 5.06 (1.22–21.02) |
| Infertility treatments (n = 15) | 0.54 (0.15–1.95) | 1.36 (0.45–4.13) | 1.17 (0.14–9.52) | 0.42 (0.05–3.28) | NC | 9.07 (2.08–39.50) |
| Sexually transmitted diseases (n = 63) | 1.40 (0.78–2.51) | 0.68 (0.35–1.33) | 1.08 (0.34–3.37) | 0.59 (0.24–1.48) | 0.44 (0.05–3.52) | 0.89 (0.19–4.22) |
| Warts | ||||||
| Genital (n = 80) | 0.62 (0.34–1.12) | 1.18 (0.66–2.11) | 0.53 (0.15–1.89) | 1.88 (0.94–3.77) | 0.85 (0.17–4.29) | 0.72 (0.15–3.55) |
| Oral (n = 8) | NC | 4.85 (1.13–20.85) | 6.00 (1.11–32.46) | NC | NC | NC |
| Skin (n = 166) | 0.96 (0.59–1.56) | 1.29 (0.77–2.14) | 1.98 (0.73–5.35) | 0.69 (0.37–1.32) | 0.87 (0.25–3.08) | 0.18 (0.04–0.87) |
| Allergies (n = 126) | 1.07 (0.64–1.77) | 0.88 (0.52–1.50) | 0.95 (0.34–2.63) | 1.13 (0.58–2.20) | 2.08 (0.49–8.89) | 2.52 (0.62–10.29) |
| Atopia (n = 43) | 0.62 (0.29–1.32) | 1.38 (0.68–2.79) | 0.34 (0.04–2.63) | 0.59 (0.20–1.74) | 1.80 (0.35–9.25) | 2.78 (0.67–11.55) |
| Vulvovaginitis (n = 48) | 1.31 (0.31–5.60) | 0.39 (0.05–3.20) | NC | NC | NC | NC |
| Menarche | ||||||
| Late (>14 years) (n = 21) | 0.96 (0.36–2.59) | 0.67 (0.22–2.08) | 3.12 (0.81–12.03) | 2.37 (0.44–12.66) | NC | 1.37 (0.16–11.38) |
| Early (<11 years) (n = 7) | 1.71 (0.37–7.83) | 0.45 (0.05–3.82) | NC | 1.01 (0.28–3.64) | NC | NC |
| Start of labour | ||||||
| Own contractions (n = 145) | 1.11 (0.66–1.87) | 0.96 (0.57–1.65) | 0.65 (0.24–1.75) | 1.12 (0.57–2.18) | 0.75 (0.20–2.86) | 0.75 (0.20–2.86) |
| Rupture of the membranes (n = 52) | 1.43 (0.75–2.74) | 1.31 (0.67–2.55) | 0.26 (0.03–2.03) | 0.43 (0.15–1.28) | 1.28 (0.26–6.37) | 1.28 (0.26–6.37) |
| Induction (n = 91) | 0.87 (0.50–1.53) | 0.79 (0.44–1.41) | 1.12 (0.40–3.13) | 1.74 (0.89–3.44) | 0.57 (0.12–2.81) | 0.72 (0.81–4.07) |
| Labour weeks | ||||||
| Early (<37 weeks) (n = 8) | 1.08 (0.19–5.99) | 2.75 (0.54–13.90) | NC | NC | NC | NC |
| Late (>40 weeks) (n = 181) | 0.82 (0.51–1.33) | 0.97 (0.59–1.62) | 2.32 (0.81–6.61) | 1.30 (0.68–2.50) | 0.51 (0.14–1.86) | 0.95 (0.28–3.17) |
| Abnormal placenta (n = 9) | 1.30 (0.30–5.56) | 0.89 (0.18.4.51) | 5.51 (1.03–29.37) | 0.85 (0.10–7.06) | NC | NC |
The significant associations are bolded