Fig. 7.

Correlation of MMP-9 expression and wound closure in vivo. a Skin wounds after wound creation (Day-0) and at Day-4 and Day-7 after respective treatments of PBS, PM1, GT/siMMP-9₁₀ or PM1(GT/siMMP-9₁₀) and representative H&E stained sections of Day-7 (scale bars = 1 mm). b Wound closure of rats at Day-7. c MMP-9 mRNA levels in skin tissues of rats by qRT-PCR at Day-0 and Day-7 after respective treatments. d MMP-9 protein levels in skin tissues of rats by Western Blot at Day-0 and Day-7 after respective treatments. e Representative images of skin wound tissues by IHC at Day-0 and Day-7 after respective treatments (scale bars = 50 μm). *P < 0.05