Table 5.
Univariable and multivariable predictors of poor quality of life and health status in adults with congenital heart disease on logistic regression
| Independent variables | Beta | Standard error | p value (Wald statistic) | OR (95%CI) |
|---|---|---|---|---|
| Univariable logistic regression | ||||
| Poor quality of life | ||||
| Women | 0.295 | 0.43 | 0.492 | 1.34 (0.58; 3.12) |
| > 30 years old | 1.065 | 0.438 | 0.015 | 2.9 (1.23; 6.84) |
| Unmarried | 0.491 | 0.433 | 0.257 | 1.63 (0.7; 3.81) |
| Less than high school | 1.121 | 0.412 | 0.007 | 3.07 (1.37; 6.88) |
| Unemployed/ had unstable employment | 1.463 | 0.475 | 0.002 | 4.3 (1.7; 10.95) |
| Complex CHD or PAH | 1.016 | 0.559 | 0.069 | 2.76 (0.92; 8.26) |
| Unrepaired CHD or repaired palliation | 0.114 | 0.474 | 0.81 | 1.12 (0.44; 2.84) |
| Life dissatisfaction | ||||
| Women | 0.014 | 0.724 | 0.984 | 1.01 (0.25; 4.19) |
| > 30 years old | − 0.198 | 0.679 | 0.77 | 0.82 (0.22; 3.1) |
| Unmarried | 1.545 | 0.687 | 0.024 | 4.69 (1.22; 18.01) |
| Less than high school | 0.148 | 0.665 | 0.824 | 1.16 (0.32; 4.27) |
| Unemployed/had unstable employment | 1.213 | 0.677 | 0.073 | 3.36 (0.89; 12.69) |
| Complex CHD or PAH | 19.087 | 10048.242 | 0.998 | – |
| Unrepaired CHD or repaired palliation | 19.175 | 8380.813 | 0.998 | – |
| Anxiety | ||||
| Women | 1.504 | 0.779 | 0.054 | 4.5 (0.98; 20.73) |
| > 30 years old | 0.606 | 0.562 | 0.281 | 1.83 (0.61; 5.51) |
| Unmarried | 0.74 | 0.521 | 0.155 | 2.1 (0.76; 5.81) |
| Less than high school | 0.984 | 0.519 | 0.058 | 2.68 (0.97; 7.41) |
| Unemployed/had unstable employment | 1.171 | 0.525 | 0.026 | 3.23 (1.15; 9.03) |
| Complex CHD or PAH | 1.312 | 0.602 | 0.029 | 3.71 (1.14; 12.08) |
| Unrepaired CHD or repaired palliation | 0.643 | 0.561 | 0.252 | 1.9 (0.63; 5.71) |
| Depression | ||||
| Women | 0.854 | 0.805 | 0.289 | 2.35 (0.49; 11.37) |
| > 30 years old | 19.627 | 6436.026 | 0.998 | – |
| Unmarried | 1.112 | 0.623 | 0.074 | 3.04 (0.9; 10.32) |
| Less than high school | 2.768 | 1.066 | 0.009 | 15.92 (1.97; 128.52) |
| Unemployed/ had unstable employment | 2.066 | 0.664 | 0.002 | 7.9 (2.15; 29.01) |
| Complex CHD or PAH | 0.767 | 0.73 | 0.293 | 2.15 (0.52; 9.01) |
| Unrepaired CHD or repaired palliation | 0.719 | 0.664 | 0.279 | 2.05 (0.56; 7.54) |
| Multivariable logistic regression | ||||
| Poor quality of life | ||||
| Step 1 | ||||
| Unemployed/ had unstable employment | 1.426 | 0.475 | 0.003 | 4.16 (1.64; 10.56) |
| Constant | -0.693 | 0.408 | 0.09 | - |
| Step 2 | ||||
| Unemployed/ had unstable employment | 1.487 | 0.486 | 0.002 | 4.43 (1.71; 11.47) |
| Complex CHD or PAH | 1.138 | 0.587 | 0.053 | 3.12 (0.99; 9.87) |
| Constant | − 1.695 | 0.676 | 0.012 | – |
| Life dissatisfaction | ||||
| Step 1 | ||||
| Unmarried | 1.533 | 0.689 | 0.026 | 4.63 (1.2; 17.86) |
| Constant | 1.344 | 0.458 | 0.003 | – |
| Anxiety defined | ||||
| Step 1 | ||||
| Unemployed/ had unstable employment | 1.141 | 0.526 | 0.03 | 3.13 (1.12; 8.76) |
| Constant | 0.636 | 0.412 | 0.123 | – |
| Step 2 | ||||
| Unemployed/ had unstable employment | 1.29 | 0.552 | 0.02 | 3.63 (1.23; 10.72) |
| Complex CHD or PAH | 1.43 | 0.636 | 0.024 | 4.19 (1.2; 14.56) |
| Constant | − 0.616 | 0.701 | 0.379 | – |
| Step 3 | ||||
| Women | 1.62 | 0.849 | 0.056 | 5.05 (0.96; 26.67) |
| Unemployed/ had unstable employment | 1.36 | 0.57 | 0.017 | 3.88 (1.27; 11.84) |
| Complex CHD or PAH | 1.58 | 0.657 | 0.016 | 4.84 (1.33; 17.54) |
| Constant | – | |||
| Depression defined as HADS-D > 10 | ||||
| Step 1 | ||||
| Unemployed/ had unstable employment | 2.039 | 0.664 | 0.002 | 7.68 (2.09; 28.25) |
| Constant | 0.865 | 0.421 | 0.04 | – |
| Step 2 | ||||
| > 30 years old | 19.192 | 6332.88 | 0.998 | – |
| Unemployed/ had unstable employment | 1.531 | 0.682 | 0.025 | 4.63 (1.22; 17.59) |
| Constant | 0.693 | 0.433 | 0.109 | – |
CHD: Congenital heart disease; PAH: Pulmonary artery hypertension; OR: Odds Ratio; CI: Confidence Interval. Poor quality of life was defined as EQ-VAS < 65; Life dissatisfaction was defined as SWLS < 20; Anxiety was defined as HADS-A > 10; Depression was defined as HADS-D > 10