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. Author manuscript; available in PMC: 2021 Jun 24.
Published in final edited form as: J Neurochem. 2020 Oct 20;157(6):1876–1896. doi: 10.1111/jnc.15200

FIGURE 6.

FIGURE 6

Cannula-guided osmotic mini-pump delivery of QDMgTx to the OB. a) Schematic of experimental timeline. CLAMS = comprehensive laboratory animal metabolic system, IPGTT = intraperitoneal glucose tolerance test. b) An Alzet osmotic mini-pump (c) was connected to bifurcated (b) cannula (a) and implanted into the OB of C57J/B6 obese mice using stereotactic guidance. c) Photomicrograph of a pair of OBs confirming placement of the bifurcated cannula; bright field, cresyl violet stain. d) Photomicrograph of an OB following incubation with 25 nM QDMgTx; DAPI stained, (a) = cannula placement, (b) = glomerular cell layer, (c) = mitral cell layer, (d) = granule cell layer; c) and d) scale bar = 5 μm.