Skip to main content
. Author manuscript; available in PMC: 2021 May 5.
Published in final edited form as: ACS Sens. 2019 Dec 13;4(12):3227–3233. doi: 10.1021/acssensors.9b01703

Figure 3.

Figure 3.

Phenylalanine-detecting E-AB sensor is rapid, quantitative, and specific. (A) The sensor responds with a time constant of less than 1 min at physiological (i.e., above 120 μM) concentrations. (B) The sensor achieves clinically relevant specificity. e.g., when it is tested against either tyrosine or a mix of five amino acids (glutamine, histidine, proline, arginine, and alanine), it does not produce a detectable signal change until the concentration rises above 10 μM. In contrast, the sensor does cross-react with tryptophan. Given, however, the physiological levels of this amino acid and the 1:1000 dilution, we employ no interference from tryptophan is expected.