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. Author manuscript; available in PMC: 2021 May 5.
Published in final edited form as: Nat Genet. 2020 Sep 28;52(10):1024–1035. doi: 10.1038/s41588-020-0696-0

Extended Data Fig. 3. Histone acetyl marks are enriched at both TSS and enhancers.

Extended Data Fig. 3

Metaplots showing peak enrichment of H3K27ac, H3K9ac and H3K122ac and corresponding 5hmC and H3K4me1 enrichments for peaks at transcriptional start sites (TSSs) (≤ 1 Kb from TSS) and enhancer (Enh) sites (> 1Kb from TSS) in (a-f) Younger, (g-l) Old and (m-r) AD brains. Histone acetyl-peaks are enriched at both TSSs and enhancers, while 5hmC and H3K4me1 mark enhancer sites.