Table 3.
Frequencies of eligible candidates for clinical trial screening by year of birth and gender
| All/YOB-gender (N) | Age | Comorbidity | Medication | MMSE | Education | All criteria |
|---|---|---|---|---|---|---|
| < 1925 (748) | 97 (13%) | 295 (39%) | 435 (58%) | 694 (93%) | 321 (43%)* | 10 (1%) |
| Men (160) | 22 (14%) | 57 (36%) | 86 (54%) | 149 (93%) | 93 (58%) | 2 (1%) |
| Women (588) | 75 (13%) | 238 (40%) | 349 (59%) | 545 (93%) | 228 (39%) | 8 (1%) |
| OR [95%CI] | 1.18 [0.70–1.99] | 0.84 [0.58–1.22] | 0.80 [0.56–1.15] | 1.02 [0.50–2.05] | 2.21 [1.54–3.16] | 0.92 [0.19–4.36] |
| 1925–1934 (3912) | 2912 (74%) | 1489 (38%) * | 2486 (64%) | 3772 (96%) | 1985 (51%)* | 426 (11%) |
| Men (1163) | 873 (75%) | 408 (35%) | 750 (64%) | 1131 (97%) | 771 (66%) | 144 (12%) |
| Women (2749) | 2,039 (74%) | 1081 (39%) | 1736 (63%) | 2641 (96%) | 1,214 (44%) | 282 (10%) |
| OR [95%CI] | 1.11 [0.94–1.30] | 0.79 [0.68–0.92] | 1.05 [0.90–1.22] | 1.14 [0.76–1.72] | 2.51 [2.17–2.90] | 1.24 [1.00–1.53] |
| 1935–1944 (3230) | 3230 (100%) | 1278 (40%) * | 2115 (65%) | 3148 (97%) | 2,047 (63%)* | 611 (19%)* |
| Men (1019) | 1016 (100%) | 383 (38%) | 690 (68%) | 998 (98%) | 760 (75%) | 215 (21%) |
| Women (2211) | 2211 (100%) | 895 (40%) | 1425 (64%) | 2150 (97%) | 1287 (58%) | 396 (18%) |
| OR [95%CI] | 1.00 [na] | 0.84 [0.72–0.98] | 1.13 [0.96–1.33] | 1.14 [0.69–1.90] | 2.11 [1.79–2.49] | 1.23 [1.02–1.48] |
| 1945–1959 (1492) | 1091 (100%) | 657 (44%) | 1003 (67%) | 1451 (97%) | 1238 (83%)* | 383 (26%) |
| Men (524) | 524 (100%) | 234 (45%) | 364 (69%) | 511 (98%) | 465 (89%) | 136 (26%) |
| Women (968) | 967 (100%) | 423 (44%) | 639 (66%) | 940 (97%) | 773 (80%) | 247 (26%) |
| OR [95%CI] | 1.00 [ na] | 1.02 [0.82–1.26] | 1.14 [0.90–1.43] | 1.12 [0.57–2.20] | 1.97 [1.44–2.69] | 1.02 [0.80–1.30] |
| 1960+ (211) | 144 (68%) | 72 (34%) | 111 (53%) | 204 (97%) | 198 (94%) | 21 (13%) |
| Men (60) | 42 (70%) | 24 (40%) | 35 (58%) | 57 (95%) | 55 (92%) | 9 (15%) |
| Women (151) | 102 (68%) | 48 (32%) | 76 (50%) | 147 (97%) | 143 (95%) | 19 (13%) |
| OR [95%CI] | 1.13 [0.58–2.20] | 1.36 [0.72–2.54] | 1.32 [0.72–2.44] | 0.73 [0.10–5.39] | 0.72 [0.15–3.37] | 1.23 [0.52–2.89] |
YOB, year of birth; MMSE, mini-mental state examination
Unless otherwise noted, data are absolute frequency (relative frequency %)
Asterisk (*) indicate p < 0.05 in test comparing eligibility between males and females by multivariable logistic regression (or univariable logistic regression for all criteria)