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. 2021 May 4;77(Pt 5):148–155. doi: 10.1107/S2053230X21004593

Figure 3.

Figure 3

Multiple sequence alignment of TtECH with its homologs performed using Clustal Omega (Sievers et al., 2011 ▸) and ESPript. TtECH (PDB entry 1uiy) is alignmed with RnECH (PDB entry 2dub), human ECH (PDB entry 2hw5), Mycobacterium tuberculosis H37Rv ECH (PDB entry 5kjp), Bacillus anthracis ECH (PDB entry 3kqf), Hymenobacter sp. PAMC 26628 ECH (PDB entry 6lvp), Legionella pneumophila ECH (PDB entry 3i47) and 3-­hydroxypropionyl-CoA dehydratase (3HPCD) from Metallosphaera sedula (PDB entry 5zai). The catalytic residues are indicated by black triangles below the sequence. The residues that determine ECH/ECI activity are marked I–III below the sequence.