Table 1. Quality of merged data.

	Intact volumes		Undamaged tomograms				Mildly damaged tomograms, c = 0.3				Moderately damaged tomograms, c = 0.2				Severely damaged tomograms, c = 0.1
			±60°		±40°		±60°		±40°		±60°		±40°		±60°		±40°
No. of crystals merged	1	5	1	5	1	5	1	5	1	5	1	5	1	5	1	5	1	5
PDB entry 6d6g (P1)
Completeness c †	0.96	0.99	0.39	0.89	0.34	0.85	0.30	0.72	0.30	0.78	0.20	0.55	0.20	0.58	0.10	0.31	0.10	0.33
R ref,φ ‡ (°)	2.4	2.6	9.2	6.2	7.4	5.5	18.9	15.0	10.4	8.8	20.2	20.9	13.6	13.6	19.5	22.1	12.3	13.6
CC(I sim, I ref)§	1.00	1.00	0.71	0.74	0.79	0.81	0.59	0.57	0.65	0.65	0.51	0.44	0.53	0.48	0.47	0.42	0.54	0.48
CC(map, model)¶	0.98	0.99	0.58	0.85	0.56	0.88	0.50	0.72	0.50	0.79	0.42	0.60	0.41	0.64	0.34	0.52	0.34	0.58
PDB entry 4bfh (P212121)
Completeness c	0.95	1.00	0.73	0.99	0.67	0.99	0.61	0.96	0.62	0.97	0.46	0.87	0.45	0.87	0.25	0.63	0.25	0.63
R ref,φ (°)	1.0	1.0	6.1	2.8	5.2	2.2	11.0	4.9	8.4	3.5	16.8	12.6	12.2	8.1	24.6	27.0	11.9	15.3
CC(I sim, I ref)	0.98	0.98	0.81	0.87	0.86	0.90	0.72	0.76	0.73	0.76	0.59	0.55	0.59	0.57	0.56	0.46	0.58	0.51
CC(map, model)	0.97	0.99	0.79	0.92	0.78	0.95	0.69	0.87	0.72	0.88	0.58	0.74	0.59	0.74	0.46	0.60	0.44	0.61

^†To a high-resolution limit of 3.3 Å. Entries show the mean value from ten runs of merging the indicated number of data sets consisting of intact volumes, undamaged tomograms or tomograms simulated with radiation damage to achieve the specified fractional P1 completeness (c).

^‡The intensity-weighted mean residual between phases from the data sets reduced to the asymmetric unit and reference phases computed directly from the atomic model.

^§The correlation coefficient between the logs of reflection intensities computed from the reduced data set and the atomic model.

^¶The correlation coefficient between the real-space maps computed from the reduced data set and the atomic model.