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| Peptide | Sequencea | Binding affinity to BCL-xL (μM) | IC50 on MTT assay (μM) |
|---|---|---|---|
| BAD | Ac-NLWAAQRYGRELRRMSDEFVDSFKK-NH2 | 0.052 | 62 |
| Cyclic peptide | Ac-1Nal-Aib-KNleADD-F(Cl2)-NH2 | 5.8 | 18 |
Italic residues denote the positions participating in the formation of lactam staple.
