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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Semin Cell Dev Biol. 2020 Oct 22;113:27–37. doi: 10.1016/j.semcdb.2020.10.001

Figure 3. Structures of damaged DNA templates and incoming dNTPs in the active sites of translesion synthesis polymerases.

Figure 3.

a.) DNA polymerase η incorporating dATP opposite the 5’ T of a thymine dimer (173). b.) DNA polymerase iota incorporating dCTP opposite an N2-ethyl-guanine (44). c.) DNA kappa iota incorporating dCTP opposite a benzo(a)pyrene diol epoxide (BPDE)-adducted guanine (174). d.) Rev1 incorporating dCTP opposite a 1,N2-propano-guanine (65).