Table 2.

Clinical Outcome Markers during Initial 48 Hours Compared to Endothelial Function Index

Outcome	Result (IQR)(n=17)	R2 peak EFI at 2–4 hours	P	R2 AUC EFI at 2–4 hours	P	R2 peak EFI at 24 hours	P	R2 AUC EFI at 24 hours	P
Lactate, mg/dL	1.8 (1.5–3.2)	0.033	0.52	0.036	0.5	0.024	0.58	0.02	0.67
IVF, mL/kg	262 (146–332.3)	0.16	0.14	0.153	0.15	0.004	0.82	0.001	0.93
UOP, mL/kg	163.8 (129–202.3)	0.024	0.58	0.075	0.32	0.384	0.01	0.433	0.008
Maximum VIS	3 (0–6.2)	0.033	0.57	0.019	0.62	0*	0.98	0*	0.99
Mean VIS	1.2 (0–1.9)	0.004	0.81	0.018	0.63	0.056	0.39	0.057	0.39
Total time intubated, hours	35.5 (15.5–91)	0.007	0.77	0.003	0.84	0.025	0.57	0.039	0.48

IVF=intravenous fluids, UOP=urine output, VIS=vasoactive inotropic score=dopamine dose (μg/kg/min) + dobutamine (μg/kg/min) + 100 × epinephrine dose (μg/kg/min) + 166 × vasopressin dose (units/kg/hr) + 100 × norepinephrine (μg/kg/min), EFI=endothelial function index, AUC=area under the curve

^*= result less than 10e⁻³

Total time intubated was collected beyond 48 hours if necessary until patient was successfully extubated for 24 hours.