Country |
Study ID |
Study design |
Random sequence generation (low = random, high = not random, unclear if not specified) |
Allocation concealment |
Baseline outcome measurement similar |
Baseline characteristics similar |
Incomplete outcome data |
Argentina |
Gertler 2014 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences |
Low except high for neonatal mortality (noted imbalance only for this outcome). |
Low: paper mentioned missingness of 3%, similar across groups. Complete‐case analyses were conducted, which may compromise results but no reporting of missingness by outcome. |
Burkina Faso |
Steenland 2017 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
High – Table 1 suggested differences between comparison and intervention existed, e.g. number of health facilities/100,000 people consistently higher in intervention than in comparator group. |
Low – see Appendix Table 4 of Steenland 2017. |
Burundi |
Bonfrer 2014a |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
High – appendix Table 6 of Bonfrer 2014a suggests differences existed between the different districts, e.g. population characteristics (poverty) varied between 28.7% and 82.3%. |
Unclear: not specified. |
Bonfrer 2014b |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
Falisse 2015 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
High – data not presented. |
Low – authors noted outcomes to focus on chosen based on completeness and sensitivity analyses conducted. |
Rudasingwa 2014 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
High – data not presented. |
Low – authors noted outcomes to focus on chosen based on completeness. |
Cambodia |
Van de Poel 2016 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
Cameroon |
Zang 2015 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
China |
Yao 2008 |
CBA |
High – as per guidance. |
High – as per guidance. |
Paper reanalyzed; reanalyzed results noted as low (analysis methods adjusted for differences). |
High – Table 1 of Yao 2008 suggests the intervention was performed in areas that were more populated and poorer compared to control. |
Unclear: not specified. |
Democratic Republic of the Congo |
Zeng 2018 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
High – Table 3 of Zeng 2018 suggests significant differences, e.g. in household size, daily spending and age of mother. |
Unclear: not specified. |
Soeters 2011 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
High – not specified. |
Unclear: not specified. |
El Salvador |
Bernal 2018 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
High – Table 2 and page 9 of Bernal 2018 highlight the differences between results‐based aid provinces and those with national funding. |
Unclear: not specified. |
Haiti |
Zeng 2013 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
High – data not presented. |
Unclear: not specified. |
Multiple – Burkina Faso, Ghana and Tanzania |
Duysburgh 2016 |
CBA |
High – as per guidance. |
High – as per guidance. |
Paper reanalyzed; reanalyzed results noted as low (analysis methods adjusted for differences). |
High – appendix Table S1 of Duysburgh 2016 suggested differences between intervention and control sites but unclear what effect this would have on outcomes. |
Unclear: not specified. |
Tanzania |
Binyaruka 2015 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
Low except for: ANC visits and IPT during ANC, outpatient visits per month < or > 5, patient assessments of staff kindness, probability of payment for delivery care, satisfaction with interpersonal care. |
High: authors noted this may have biased results. |
Binyaruka 2017 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
Low except for: availability and stockouts of medicines and medical supplies |
Unclear: not specified. |
Binyaruka 2018b |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
Low except for: ANC visits and IPT during ANC, outpatient visits per month < or > 5, patient assessments of staff kindness, probability of payment for delivery care, satisfaction with interpersonal care. |
High: authors noted that this may have biased results. |
Mayumana 2017 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
Low except for: medical supply stockouts, disruptions due to broken equipment, governance outcomes (committee meetings, content of supervision, existence of community health fund). |
High: authors noted that this may have biased results. |
Zimbabwe |
Das 2017 |
CBA |
High – as per guidance. |
High – as per guidance. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
High: subset analyses with particularly small samples. |
Benin |
Lagarde 2015 |
Quasi/non‐randomized trial |
Unclear: not specified. |
Unclear: not specified. |
High – analyses methods did not adjust for baseline differences in outcomes, but do adjusted for facility and health worker differences. |
High – appendix Table 6 of Lagarde 2015 suggested differences exist between the different districts, e.g. population characteristics (poverty) varied between 28.7% and 82.3%. |
Unclear: not specified. |
Cameroon |
de Walque 2017 |
Quasi/non‐randomized trial |
Low – sequence described in sufficient detail. |
Low – assignment by province/district/cluster. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
China |
Powell‐Jackson 2014 |
Quasi/non‐randomized trial |
High – no randomization, though matching occurred. |
Low – assignment by province/district/cluster. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
Sun 2016 |
Quasi/non‐randomized trial |
High – randomization compromised. |
Low – assignment by province/district/cluster. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
Peru |
Cruzado de la Vega 2017 |
Quasi/non‐randomized trial |
High – no randomization. |
Low – assignment by province/district/cluster. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
Rwanda |
Basinga 2011 |
Quasi/non‐randomized trial |
High – randomization compromised. |
Low – assignment by province/district/cluster. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
Lannes 2016 |
Quasi/non‐randomized trial |
High – randomization compromised. |
Low – assignment by province/district/cluster. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
Priedeman Skiles 2013 |
Quasi/non‐randomized trial |
High – randomization compromised. |
Low – assignment by province/district/cluster. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
Priedeman Skiles 2015 |
Quasi/non‐randomized trial |
High – randomization compromised. |
Low – assignment by province/district/cluster. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
Sherry 2017 |
Quasi/non‐randomized trial |
High – randomization compromised. |
Low – assignment by province/district/cluster. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
Lannes 2015 |
Quasi/non‐randomized trial |
High – randomization compromised. |
Low – assignment by province/district/cluster. |
Unclear: not specified. |
High – not specified. |
Unclear: not specified, using data from Basinga 2011. |
Gertler 2013 |
Quasi/non‐randomized trial |
High – randomization compromised. |
Low – assignment by province/district/cluster. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Low – authors noted similar levels of attrition. |
de Walque 2015 |
Quasi/non‐randomized trial |
High – randomization compromised. |
Low – assignment by province/district/cluster. |
Low – analysis methods adjusted for differences. |
Low – comparable. |
Unclear: not specified. |
Swaziland |
Kliner 2015 |
Quasi/non‐randomized trial |
High – no randomization. |
High – allocation was pragmatic. |
Low – analysis methods adjusted for differences. |
High – Table 2 of Kliner 2015 suggested differences in populations and outcomes exist. |
Unclear: not specified. |
Tanzania |
Brock 2018 |
Quasi/non‐randomized trial |
Low – sequence described in sufficient detail. |
Low – assignment by healthcare professional, done after baseline assessment. |
Low – comparable. |
High – Tables 2 and 3 of Brock 2018 suggested some differences between providers and patients. |
Low – dropout before assignment 12%, but after only 3%. |
Zimbabwe |
Friedman 2016b |
Quasi/Non‐randomized trial |
High – no randomization, though stratification and matching. |
High – allocation was done by Ministry if Health via matching. |
Low – analysis methods adjusted for differences. |
Low – comparable. (Appendix 3 of Friedman 2016b tested parallel trends, though baseline characteristics were dissimilar at times). |
Unclear: not specified (authors noted that for household expenditure data there was high missingness). |
ANC: antenatal care; CBA: controlled before‐after; IPT: intermittent preventive treatment. |