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Mechanism of antifibrotic effect of valsartan/sacubitril (Entresto). (a) Mechanistic map of major effectors of val/sac in the fibroblast signaling network. (b) Predicted effect of knockdown of effectors of val/sac activity on collagen mRNA and collagen area fraction at day 7 and day 42 of post‐myocardial infarction simulation
