Table 1.

Comparison of lipid metabolism related indexes in chow-fed and HFD-fed mice

Group	TG (mM)	TC (mM)	HDL-C (mM)	LDL-C (mM)	HDL-C/LDL-C	ALT (U/L)	AST (U/L)
chow	1.04 ± 0.08	2.96 ± 0.31	2.95 ± 0.36	0.27 ± 0.03	11.15 ± 2.23	80.52 ± 13.39	93.80 ± 14.21
HFD	1.42 ± 0.15∗∗∗	6.04 ± 0.42∗∗∗	3.26 ± 0.32	0.82 ± 0.11∗∗∗	4.03 ± 0.58∗∗∗	130.48 ± 16.57∗∗∗	150.15 ± 20.46∗∗∗

∗∗∗p < 0.001 versus chow-fed mice. Measurement data were presented as the mean ± standard deviation, and data comparison between two groups was conducted using independent sample t test. n = 10. HFD, high-fat diet; TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ALT, alanine aminotransferase; AST, aspartate aminotransferase; PPARα, peroxisome proliferator activated receptor alpha; sh-NC, short hairpin RNA-negative control.