Table 3.
Pooled AUC, Q∗ index, sensitivity, specificity, LR+, LR−, and DOR for diagnosing ANG in the urine of patients with bladder cancer based on the random effects model.
| No. studies | AUC | Q ∗ | Variables | Pooled (95% CI) | I 2 (%) | Cochran's-Q | τ 2 | p value |
|---|---|---|---|---|---|---|---|---|
| 4 | 0.789 | 0.726 | Sensitivity | 0.710 (0.662-0.753) | 20.8% | 3.79 | NA | 0.285 |
| Specificity | 0.780 (0.736-0.819) | 92.1% | 37.95 | NA | <0.0001 | |||
| LR+ | 3.344 (2.021-5.533) | 82.7% | 17.33 | 0.197 | 0.001 | |||
| LR− | 0.376 (0.320-0.441) | 0% | 53.67 | 0 | 0.521 | |||
| DOR | 9.992 (4.691–21.282) | 77.4% | 13.26 | 0.443 | 0.004 |
AUC: area under the curve; I2: I-squared; χ2: Chi-squared; τ2: tau-squared; NA: not assessed; LR+: positive likelihood ratio; LR−: negative likelihood ratio; DOR: diagnostic odds ratio; CI: confidence interval. I2 = 100% × (Q − df)/Q, where Q is the Chi-squared statistic and df is the degree of freedom of Q statistic.