Figure 3.

Glycogen accumulation was observed in MED13-LKO liver under fructose feeding. A) Representative H&E stained liver sections of Med13^fl/fl and MED13-LKO after overnight fasting followed by chow feeding supplemented with 30% fructose containing water for 4 h. B) Representative periodic acid Schiff (PAS)-stained liver sections of the Med3^fl/fl and MED13-LKO mice. C) Hepatic glycogen measurement from the Med13^fl/fl and MED13-LKO mice under fasted or ad libitum fed supplemented with either water or water with 30% fructose or 30% sucrose conditions. D) Serum insulin levels of WT mice after feeding (n = 8 per group). Statistical significance was determined by one-way ANOVA followed by the Turkey-Kramer multiple comparisons test. Bars with the same letter are not significantly different.