Table 2.

Temporal changes in blood and kidney parameters

N = 223	Baseline	3 months	6 months	12 months
Body weight (kg)	77.9 ± 1.5	75.3 ± 1.5***	75.7 ± 1.6***	76.3 ± 1.5*
BMI (kg/m2)	28.4 ± 0.5	27.6 ± 0.5*	27.7 ± 0.5*	27.8 ± 0.4*
Systolic BP (mmHg)	138.2 ± 1.2	135.7 ± 1.4*	134.8 ± 1.3*	133.3 ± 1.4**
Diastolic BP (mmHg)	78.9 ± 1.0	77.4 ± 1.1	76.8 ± 1.0	76.6 ± 1.0
HbA1c (%)	7.89 ± 0.08	7.36 ± 0.06***	7.36 ± 0.06***	7.32 ± 0.07***
LDL-cholesterol (mg/dL)	108.4 ± 6.4	99.9 ± 2.0	100.1 ± 2.1	99.8 ± 2.1
Serum Mg (mg/dL)	1.93 ± 0.02	2.07 ± 0.02**	2.05 ± 0.02**	2.01 ± 0.02**
eGFR (mL/min/1.73m2)	73.2 ± 1.6	69.5 ± 1.6***	69.7 ± 1.6***	70.2 ± 1.7*
UACR (mg/g)	67.6 (14.6–411.7)	69.8 (16.0–281.0)	53.8 (13.8–301.5)*	60.4 (13.6–276.2)

UACR, urine albumin/creatinine ratio

*p < 0.05, **p < 0.01, ***p < 0.005 vs. baseline