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. 2021 Apr 7;593(7857):101–107. doi: 10.1038/s41586-021-03420-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a–d, Structure and sequence identity of the chimpanzee (H1) (a), chimpanzee (H2) (b), orangutan (c) and macaque (d) chromosome 8 centromeres. Each centromere has a mirrored organization consisting of four or five distinct evolutionary layers. The size of each centromeric region is consistent with microscopic analyses, showing increasingly bright DAPI staining with increasing centromere size. See Supplementary Figs. 10 and 11 for sequence identity heat maps plotted on the same colour scale. H1, haplotype 1; H2, haplotype 2. Scale bar, 1 μm.