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. 2021 Apr 7;593(7857):101–107. doi: 10.1038/s41586-021-03420-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — a, Schematic showing the first and last megabase of the CHM13 chromosome 8 assembly. A dot plot of the terminal 5 kb shows high sequence identity among the last approximately 2.5 kb of the chromosome, consistent with the presence of a high-identity telomeric repeating unit. b, c, Number of TTAGGG telomeric repeats in the last 5 kb of the p-arm (b) and q-arm (c) in chromosome 8. The p-arm has a gradual transition to pure TTAGGG repeats over nearly 1 kb, whereas the q-arm has a very sharp transition to pure TTAGGG repeats that occurs over nearly 300 bp.