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. 2021 May;6(5):590–598. doi: 10.1016/j.bpsc.2020.12.012

Figure 3.

Figure 3

(A) Skin conductance responses (SCRs) in the initial threat conditioning phase (acquisition) on day 1, conducted before serotonergic challenge. There were no differences between the future placebo and future acute tryptophan depletion (ATD) groups, and both groups showed significant threat conditioning to both paired conditioned stimuli (CS+s) compared with the CS−, as predicted. This equivalent baseline conditioning on day 1 enabled testing the effects of ATD on its retention on day 2. Brackets denote follow-up t tests contrasting stimuli within group, after observing a main effect of stimulus. ∗∗∗p < .001. Error bars indicate ±1 SE. (B) SCRs in the extinction phase on day 1. Smaller brackets refer to the beginning and end of extinction, and the larger bracket denotes a mild reduction in SCRs in late compared with early extinction. ∗p < .05. Error bars indicate ±1 SE. Raw data (following transformation) (see Supplement) are displayed. CS+E, extinguished CS+; CS+N, not extinguished CS+; n.s., not significant.