Table 2.
Participant age and disease characteristics
| Characteristics | Mild (n=5) | Moderate (n=5) | Severe (n=26) | Inhibitor (n=7) (all severe) |
Total group (n=43) |
|---|---|---|---|---|---|
| Median age (years) (range) | 12.6 (9.3–14.6) | 9.1 (6.7–15.1) | 10.3 (6.3–14.6) | 8.6 (6.23–11.15) | 10.0 (6.2–15.1) |
| Diagnosis: | |||||
| Haemophilia A | 5 | 2 | 20 | 7 | 34 |
| Haemophilia B | 0 | 3 | 6 | 0 | 9 |
| Treatment: | |||||
| Prophylaxis | 2 | 4 | 26 | n/a | 32 |
| On demand | 3 | 1 | 0 | 0 | 4 |
| Novel treatment | n/a | n/a | n/a | 7 | 7 |
| Number of children with bleeds in previous year | 2 | 0 | 10 | 0 | 12 |
| Median Annual Bleed Rate (ABR) (range) | 0 (0–1) | n/a | 0 (0–3) | n/a | 0 (0–3) |
| Known joint arthropathy | 0 | 0 | 0 | 1 (right knee) | 1 |
| Median HJHS scorea (range) | 1 (0–1) | 0 (0–2) | 1 (0–12) | 3 (0–8) | 1 (0–12) |
aOf 43 boys 16 had HJHS lower limb scores >1, of which, median HJHS score=2 (range 1–6)